
2026 Week 1 college football picks, predictions: Wisconsin-Notre Dame, Louisville-Ole Miss best bets
SportsLine's model reveals its Week 1 college football picks and best bets for Sunday, September 6
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SportsLine's model reveals its Week 1 college football picks and best bets for Sunday, September 6

SportsLine's Zack Cimini reveals his picks for the Louisville Cardinals vs. Ole Miss Rebels matchup on Sunday

Bettors can use college football sportsbook promos at the best CFB betting sites and CFB betting apps for Week 1

Notre Dame's quest to earn a College Football Playoff berth begins against Wisconsin, which is trying to return to prominence

A pair of ranked teams meet in Nashville to open their 2026 college football seasons. Here's everything bettors need to know

SportsLine's model has simulated every game 10,000 times and locked in its Week 1 NFL score predictions

SportsLine's advanced model has locked in its Week 1 college football predictions from 10,000 simulations

Sign up and bet with the latest FanDuel promo code on Sunday to get your bonus bets

Western Michigan leadership accepted the Big Ten replay ruling that led to Michigan's walk-off touchdown, choosing to move forward rather than fight a controversial finish