Inter Milan will be without two key players as they head to Rome for Saturday's Serie A clash against Lazio at the Stadio Olimpico. The reigning champions, who have already secured the Scudetto with three games remaining, confirmed that both Francesco Pio Esposito and Hakan Calhanoglu did not travel with the squad.

Young Italy international Esposito is sidelined with back pain, with manager Cristian Chivu opting to rest him as a precaution. The decision comes with an eye on next week's Coppa Italia Final—a rematch against the same Lazio side. Calhanoglu, meanwhile, has been out since late April with a soleus injury and is also expected to miss that cup decider, leaving a creative void in Inter's midfield.

On a brighter note for Inter, Brazilian winger Luis Henrique has recovered from his own injury and will be available for selection in Rome. For Lazio, the stakes remain high as they sit four points outside a Conference League qualification spot, making this a must-win fixture for the Biancocelesti.

These two sides will meet again on May 13 in the Coppa Italia Final, adding extra spice to Saturday's league encounter. As Inter look to finish their title-winning campaign in style, fans will be watching closely to see how Chivu's rotated lineup handles a motivated Lazio side at the Olimpico.