It’s the heart of May, and for college lacrosse fans, that means one thing: NCAA Tournament quarterfinal weekend is here. The Syracuse Orange are heading to Long Island for a pivotal showdown with the North Carolina Tar Heels—their third and final meeting of the season. The stakes couldn’t be higher: win and keep the dream alive, lose and head home.

The action takes place at James M. Shuart Stadium on the campus of Hofstra University in Hempstead. Syracuse and North Carolina are set as the second quarterfinal of the day, following the opening matchup between Johns Hopkins and Notre Dame at noon. Expect the Orange and Tar Heels to face off around 2:30 PM ET, or roughly 40 minutes after the first game wraps up. You can catch all the action on ESPN U.

North Carolina enters this contest searching for consistency. The Tar Heels dropped two of their last three regular-season games, including lopsided losses to Duke (16 goals allowed) and Virginia in the ACC title game (another 16 goals against). The one bright spot in that stretch? A win over Syracuse. But those defensive struggles forced a bold move: a switch in goal from freshman Josh Marcus to senior Kent Goode.

Here’s where it gets interesting. Goode had never started a single game in his four-year career until UNC’s first-round matchup against UAlbany. And how did that go? The Tar Heels rolled to a 24-6 victory, with Goode recording eight saves and allowing just four goals in three quarters of work. That performance has everyone wondering: will they stick with the hot hand against a tougher Syracuse offense, or turn back to Marcus, who already has two games of experience against the Orange this season?

On the Syracuse side, all eyes are on the injury report. The biggest question mark revolves around Owen Duffy, who missed the first-round game with a hamstring injury he suffered in the ACC title game against Virginia. Surprisingly, the Orange didn’t miss a beat, cruising past the Great Danes. But Duffy’s status remains uncertain as the team prepares for a much stiffer test. No official word has come out on the severity of his injury, but early indications suggest he won’t be at 100 percent if he does play.

With both teams battling injuries, lineup changes, and the pressure of a win-or-go-home scenario, this quarterfinal has all the makings of a classic. Whether you’re a die-hard fan or just tuning in, this is the kind of matchup that defines March lacrosse—and May, too.