Mets vs. Dodgers odds, line, prediction: 2026 MLB picks for Wednesday, April 15 with Shohei Ohtani pitching

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Mets vs. Dodgers odds, line, prediction: 2026 MLB picks for Wednesday, April 15 with Shohei Ohtani pitching

Mets vs. Dodgers odds, line, prediction: 2026 MLB picks for Wednesday, April 15 with Shohei Ohtani pitching

SportsLine's model simulated the New York Mets vs. Los Angeles Dodgers 10,000 times and revealed its MLB predictions for Wednesday's matchup with Shohei Ohtani on the hill

Mets vs. Dodgers odds, line, prediction: 2026 MLB picks for Wednesday, April 15 with Shohei Ohtani pitching

SportsLine's model simulated the New York Mets vs. Los Angeles Dodgers 10,000 times and revealed its MLB predictions for Wednesday's matchup with Shohei Ohtani on the hill

Wednesday night's MLB action features a marquee pitching matchup as Shohei Ohtani and the Los Angeles Dodgers host the struggling New York Mets. The Dodgers, riding high after winning the first two games of the series, look to complete the sweep, while the Mets desperately need to snap a seven-game losing skid.

All eyes will be on the mound at Dodger Stadium, where Shohei Ohtani makes his third start of the season. The two-way superstar has been dominant, sporting a pristine 0.00 ERA. He's coming off a strong six-inning outing against Toronto and will be looking to continue that form. The Mets counter with Clay Holmes, who brings a solid 1.50 ERA into this tough assignment against a potent Dodgers lineup.

The betting markets heavily favor the home team, with the Dodgers listed as -193 favorites on the money line. The total runs line is set at 7.5. For those looking for data-driven insights, SportsLine's projection model, which simulates every game 10,000 times, has analyzed this contest. The model, which was profitable on top MLB picks last season, has identified a specific trend for this game.

After running its simulations, the model is projecting the game to go Over the 7.5 total runs. While Ohtani has been brilliant on the mound, his history against the Mets as a hitter is notable—he boasts a .294 average with five homers in 18 career games. This offensive prowess, combined with the pressure on Mets starter Clay Holmes (who has a 4.35 ERA lifetime against LA), suggests runs could be on the board from both sides. Francisco Lindor is expected to be a key figure for the Mets' offense as they try to solve Ohtani and turn their fortunes around.

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