Tuesday night's MLB slate is packed with exciting matchups, and DraftKings has released its list of the five most-bet players to go deep. Let's dive into the trends and what makes each slugger a popular pick tonight.
Leading the pack is Chicago White Sox rookie sensation Munetaka Murakami. The 26-year-old Japanese import has been a game-changer for the Pale Hose, smashing 15 home runs this season—good for third in the majors and making him the +150 favorite for AL Rookie of the Year. Tonight, the White Sox host the Royals at Rate Field, where winds are blowing hard (20+ mph) from left to right, creating prime conditions for fly balls to carry. Murakami has five homers at home this season, and while he's never faced Kansas City's Stephen Kolek, the wind is on his side. Just keep an eye on the rain forecast—it's expected to hold off.
Next up is Minnesota's Byron Buxton. The Twins welcome Miami to Target Field, and Marlins starter Eury Perez has struggled on the road, posting a 7.48 ERA with three home runs allowed in three away starts. Buxton, who hit a career-high 35 homers in 2025, already has 13 this season and is heating up with two dingers in his last three games. Winds are blowing out to right in Minneapolis, adding to the appeal. Buxton is 0-for-3 career against Perez, but the matchup favors the slugger tonight.
Toronto's Kazuma Okamoto is drawing heavy action as well. The Blue Jays' Japanese infielder is on a 10-game hitting streak, batting .333 with five homers in May. He faces a tough test in Tampa Bay's Shane McClanahan (4-2, 2.60 ERA), who has allowed just one homer all season. However, Okamoto is 1-for-2 with a double and a walk against him, and with no weather concerns in Toronto, bettors are banking on his hot streak to continue.
Rounding out the list are a pair of familiar names: New York Yankees' Aaron Judge and Baltimore's Gunnar Henderson. Judge typically leads these lists, but tonight he's not the top dog—perhaps due to the tough matchup at Camden Yards. Henderson, meanwhile, has been a bright spot for the Orioles and is a popular pick to go deep at home.
Whether you're chasing the wind-aided power in Chicago or the hot bats in Toronto, tonight's slate offers plenty of opportunities for home run action.