CLEVELAND — The reigning American League Central Division champion Cleveland Guardians continue a three-game series with the Houston Astros on Tuesday, April 21.
The Guardians lost 9-2 to the Astros on Monday, April 20.
The Guardians (13-11) hold a half game lead over the Detroit Tigers (12-11) in the American League Central Division. The Astros (9-15) are at the bottom of the AL West.
Follow along here throughout the game for live updates, highlights and analysis:
Apr 20, 2026; Cleveland, Ohio, USA; Cleveland Guardians starting pitcher Slade Cecconi (44) throws a pitch against the Houston Astros during the first inning at Progressive Field. Mandatory Credit: Ken Blaze-Imagn ImagesApr 20, 2026; Cleveland, Ohio, USA; Houston Astros first baseman Christian Walker (8) rounds the bases after hitting a home run against the Cleveland Guardians during the first inning at Progressive Field. Mandatory Credit: Ken Blaze-Imagn ImagesApr 20, 2026; Cleveland, Ohio, USA; Houston Astros starting pitcher Spencer Arrighetti (41) throws a pitch against the Cleveland Guardians during the first inning at Progressive Field. Mandatory Credit: Ken Blaze-Imagn ImagesApr 20, 2026; Cleveland, Ohio, USA; Cleveland Guardians first baseman Kyle Manzardo (9) hits a single during the first inning against the Houston Astros at Progressive Field. Mandatory Credit: Ken Blaze-Imagn ImagesApr 20, 2026; Cleveland, Ohio, USA; Cleveland Guardians third baseman Jose Ramirez (11) celebrates after scoring against the Houston Astros during the first inning at Progressive Field. Mandatory Credit: Ken Blaze-Imagn Images1 / 5Cleveland Guardians home series vs. Houston AstrosApr 20, 2026; Cleveland, Ohio, USA; Cleveland Guardians starting pitcher Slade Cecconi (44) throws a pitch against the Houston Astros during the first inning at Progressive Field. Mandatory Credit: Ken Blaze-Imagn Images1 / 5Cleveland Guardians home series vs. Houston AstrosApr 20, 2026; Cleveland, Ohio, USA; Cleveland Guardians starting pitcher Slade Cecconi (44) throws a pitch against the Houston Astros during the first inning at Progressive Field. Mandatory Credit: Ken Blaze-Imagn Images2 / 5Cleveland Guardians home series vs. Houston AstrosApr 20, 2026; Cleveland, Ohio, USA; Houston Astros first baseman Christian Walker (8) rounds the bases after hitting a home run against the Cleveland Guardians during the first inning at Progressive Field. Mandatory Credit: Ken Blaze-Imagn Images3 / 5Cleveland Guardians home series vs. Houston AstrosApr 20, 2026; Cleveland, Ohio, USA; Houston Astros starting pitcher Spencer Arrighetti (41) throws a pitch against the Cleveland Guardians during the first inning at Progressive Field. Mandatory Credit: Ken Blaze-Imagn Images4 / 5Cleveland Guardians home series vs. Houston AstrosApr 20, 2026; Cleveland, Ohio, USA; Cleveland Guardians first baseman Kyle Manzardo (9) hits a single during the first inning against the Houston Astros at Progressive Field. Mandatory Credit: Ken Blaze-Imagn Images5 / 5Cleveland Guardians home series vs. Houston AstrosApr 20, 2026; Cleveland, Ohio, USA; Cleveland Guardians third baseman Jose Ramirez (11) celebrates after scoring against the Houston Astros during the first inning at Progressive Field. Mandatory Credit: Ken Blaze-Imagn ImagesWhen do the Guardians play today?First pitch is 6:10 p.m. Tuesday, April 21.
The Cleveland Guardians vs. Houston Astros game is available on TV via Guardians.TV and Space City Home Network. Streaming is available on MLB.TV and Fubo, which offers a free trial.
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The Guardians will send left-hander Parker Messick (3-0, 1.05 ERA) to the mound and Houston will counter with right-hander Ryan Weiss (0-2, 6.75 ERA).
Apr 14, 2026; St. Louis, Missouri, USA; St. Louis Cardinals catcher Iv‡n Herrera (48) tags out Cleveland Guardians first baseman Kyle Manzardo (9) during the fourth inning at Busch Stadium.Cleveland Guardians center fielder Daniel Schneemann, left, almost collides with right fielder Angel Martinez as he catches a fly ball hit by St. Louis Cardinals' Alec Burleson (not pictured) on April 13, 2026, in St. Louis, Missouri.Cleveland Guardians catcher Austin Hedges (27) pitches against the Atlanta Braves during the ninth inning on April 12, 2026, in Cumberland, Georgia.Cleveland Guardians starting pitcher Parker Messick throws against the Atlanta Braves on April 11, 2026, in Atlanta, Georgia.Apr 10, 2026; Atlanta, Georgia, USA; Cleveland Guardians third baseman Jose Ramirez (11) in the dugout against the Atlanta Braves in the second inning at Truist Park. Mandatory Credit: Brett Davis-Imagn ImagesApr 8, 2026; Cleveland, Ohio, USA; Cleveland Guardians left fielder Angel Martinez (1) celebrates after hitting a grand slam during the eighth inning against the Kansas City Royals at Progressive Field. Mandatory Credit: Ken Blaze-Imagn ImagesCleveland Guardians rookie Juan Brito hits a double for his first career hit during the second inning of his Major League debut against the Kansas City Royals on April 7, 2026, in Cleveland.Cleveland Guardians third baseman Jose Ramirez acknowledges the fans after becoming the franchise's all time leader in games played during a game against the Kansas City Royals on April 6, 2026, in Cleveland.Cleveland Guardians' CJ Kayfus celebrates his solo home run with designated hitter Chase DeLauter (24) in the eighth inning against the Chicago Cubs on April 5, 2026, in Cleveland.Apr 5, 2026; Cleveland, Ohio, USA; Cleveland Guardians shortstop Brayan Rocchio (4) makes a catch in the fifth inning against the Chicago Cubs.Guardians third baseman Jose Ramirez slides safely into second base during the home opener against the Chicago Cubs, April 3, 2026, in Cleveland.Apr 1, 2026; Los Angeles, California, USA; Cleveland Guardians second baseman Daniel Schneemann (10) steals third base during the third inning against the Los Angeles Dodgers at Dodger Stadium. Mandatory Credit: Jayne Kamin-Oncea-Imagn ImagesMar 31, 2026; Los Angeles, California, USA; Los Angeles Dodgers two-way player Shohei Ohtani (17) throws to the plate during the first inning against the Cleveland Guardians at Dodger Stadium. Mandatory Credit: Gary A. Vasquez-Imagn ImagesMar 30, 2026; Los Angeles, California, USA; Cleveland Guardians catcher Austin Hedges (27) reacts after hitting a double against the Los Angeles Dodgers in the third inning at Dodger Stadium. Mandatory Credit: Kirby Lee-Imagn ImagesMar 29, 2026; Seattle, Washington, USA; Seattle Mariners center fielder Julio Rodriguez (44) scores a run off an RBI double hit by Seattle Mariners left fielder Randy Arozarena (56) during the fifth inning at T-Mobile Park. Mandatory Credit: Steven Bisig-Imagn ImagesMar 28, 2026; Seattle, Washington, USA; Cleveland Guardians designated hitter Chase DeLauter (24) celegbrates with centerfielder Steven Kwan (38) after hitting a two-run home run during the tenth inning against the Seattle Mariners at T-Mobile Park.Mar 27, 2026; Seattle, Washington, USA; Cleveland Guardians right fielder Chase DeLauter (24) rounds the bases after hitting a solo home run during the first inning against the Seattle Mariners at T-Mobile Park. Mandatory Credit: Stephen Brashear-Imagn ImagesMar 26, 2026; Seattle, Washington, USA; Cleveland Guardians right fielder Chase DeLauter (24) runs the bases after hitting a home run against the Seattle Mariners during the first inning at T-Mobile Park. Mandatory Credit: Steven Bisig-Imagn Images1 / 18Cleveland Guardians photo of the day: Best images from each 2026 gameApr 14, 2026; St. Louis, Missouri, USA; St. Louis Cardinals catcher Iv‡n Herrera (48) tags out Cleveland Guardians first baseman Kyle Manzardo (9) during the fourth inning at Busch Stadium.1 / 18Cleveland Guardians photo of the day: Best images from each 2026 gameApr 14, 2026; St. Louis, Missouri, USA; St. Louis Cardinals catcher Iv‡n Herrera (48) tags out Cleveland Guardians first baseman Kyle Manzardo (9) during the fourth inning at Busch Stadium.2 / 18Cleveland Guardians photo of the day: Best images from each 2026 gameCleveland Guardians center fielder Daniel Schneemann, left, almost collides with right fielder Angel Martinez as he catches a fly ball hit by St. Louis Cardinals' Alec Burleson (not pictured) on April 13, 2026, in St. Louis, Missouri.3 / 18Cleveland Guardians photo of the day: Best images from each 2026 gameCleveland Guardians catcher Austin Hedges (27) pitches against the Atlanta Braves during the ninth inning on April 12, 2026, in Cumberland, Georgia.4 / 18Cleveland Guardians photo of the day: Best images from each 2026 gameCleveland Guardians starting pitcher Parker Messick throws against the Atlanta Braves on April 11, 2026, in Atlanta, Georgia.5 / 18Cleveland Guardians photo of the day: Best images from each 2026 gameApr 10, 2026; Atlanta, Georgia, USA; Cleveland Guardians third baseman Jose Ramirez (11) in the dugout against the Atlanta Braves in the second inning at Truist Park. Mandatory Credit: Brett Davis-Imagn Images6 / 18Cleveland Guardians photo of the day: Best images from each 2026 gameApr 8, 2026; Cleveland, Ohio, USA; Cleveland Guardians left fielder Angel Martinez (1) celebrates after hitting a grand slam during the eighth inning against the Kansas City Royals at Progressive Field. Mandatory Credit: Ken Blaze-Imagn Images7 / 18Cleveland Guardians photo of the day: Best images from each 2026 gameCleveland Guardians rookie Juan Brito hits a double for his first career hit during the second inning of his Major League debut against the Kansas City Royals on April 7, 2026, in Cleveland.8 / 18Cleveland Guardians photo of the day: Best images from each 2026 gameCleveland Guardians third baseman Jose Ramirez acknowledges the fans after becoming the franchise's all time leader in games played during a game against the Kansas City Royals on April 6, 2026, in Cleveland.9 / 18Cleveland Guardians photo of the day: Best images from each 2026 gameCleveland Guardians' CJ Kayfus celebrates his solo home run with designated hitter Chase DeLauter (24) in the eighth inning against the Chicago Cubs on April 5, 2026, in Cleveland.10 / 18Cleveland Guardians photo of the day: Best images from each 2026 gameApr 5, 2026; Cleveland, Ohio, USA; Cleveland Guardians shortstop Brayan Rocchio (4) makes a catch in the fifth inning against the Chicago Cubs.11 / 18Cleveland Guardians photo of the day: Best images from each 2026 gameGuardians third baseman Jose Ramirez slides safely into second base during the home opener against the Chicago Cubs, April 3, 2026, in Cleveland.12 / 18Cleveland Guardians photo of the day: Best images from each 2026 gameApr 1, 2026; Los Angeles, California, USA; Cleveland Guardians second baseman Daniel Schneemann (10) steals third base during the third inning against the Los Angeles Dodgers at Dodger Stadium. Mandatory Credit: Jayne Kamin-Oncea-Imagn Images13 / 18Cleveland Guardians photo of the day: Best images from each 2026 gameMar 31, 2026; Los Angeles, California, USA; Los Angeles Dodgers two-way player Shohei Ohtani (17) throws to the plate during the first inning against the Cleveland Guardians at Dodger Stadium. Mandatory Credit: Gary A. Vasquez-Imagn Images14 / 18Cleveland Guardians photo of the day: Best images from each 2026 gameMar 30, 2026; Los Angeles, California, USA; Cleveland Guardians catcher Austin Hedges (27) reacts after hitting a double against the Los Angeles Dodgers in the third inning at Dodger Stadium. Mandatory Credit: Kirby Lee-Imagn Images15 / 18Cleveland Guardians photo of the day: Best images from each 2026 gameMar 29, 2026; Seattle, Washington, USA; Seattle Mariners center fielder Julio Rodriguez (44) scores a run off an RBI double hit by Seattle Mariners left fielder Randy Arozarena (56) during the fifth inning at T-Mobile Park. Mandatory Credit: Steven Bisig-Imagn Images16 / 18Cleveland Guardians photo of the day: Best images from each 2026 gameMar 28, 2026; Seattle, Washington, USA; Cleveland Guardians designated hitter Chase DeLauter (24) celegbrates with centerfielder Steven Kwan (38) after hitting a two-run home run during the tenth inning against the Seattle Mariners at T-Mobile Park.17 / 18Cleveland Guardians photo of the day: Best images from each 2026 gameMar 27, 2026; Seattle, Washington, USA; Cleveland Guardians right fielder Chase DeLauter (24) rounds the bases after hitting a solo home run during the first inning against the Seattle Mariners at T-Mobile Park. Mandatory Credit: Stephen Brashear-Imagn Images18 / 18Cleveland Guardians photo of the day: Best images from each 2026 gameMar 26, 2026; Seattle, Washington, USA; Cleveland Guardians right fielder Chase DeLauter (24) runs the bases after hitting a home run against the Seattle Mariners during the first inning at T-Mobile Park. Mandatory Credit: Steven Bisig-Imagn ImagesAmerican League Central Division standingsGuardians 13-11
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Akron Beacon Journal sports writer Michael Beaven can be reached by email at mbeaven@thebeaconjournal.
This article originally appeared on Akron Beacon Journal: Cleveland Guardians lineup today, score, live updates vs. Astros