Friday night baseball is heating up with Rivalry Weekend, and that means prime opportunities for MLB fans and bettors alike. High-stakes matchups like Yankees vs. Mets and Dodgers vs. Angels are on the slate, offering plenty of action for those looking to spice up their game-day experience. Among the most exciting prop bets are MLB home run picks, and if you're looking for an edge, SportsLine data analyst Jacob Fetner has been on fire—racking up 50 units on his home run selections last year. For Friday, May 15, he's unveiled three top-tier HR prop bets, and Baltimore Orioles shortstop Gunnar Henderson (+390) is a standout pick.

Henderson has already crushed two home runs in 23 at-bats against Nationals starter Zack Littell, and Fetner sees more fireworks ahead. "Gunnar Henderson (bats L) has the platoon advantage against right-handed Zack Littell," Fetner notes. "Even though Henderson is batting .207 with a .648 OPS vs RHP this season, six of his nine home runs have come against righties. Littell has allowed nine home runs in 96 plate appearances to left-handed hitters, and he's struggled overall with a 1-4 record and 6.94 ERA. Henderson has been in a slump, batting just .159 over his last 10 games, but we think he's due to break out."

Another intriguing name on Fetner's radar is Mickey Moniak of the Angels. "Mickey Moniak is hitting .343 with a 1.139 OPS against right-handed pitchers this season, with 10 of his 12 home runs coming off RHPs," Fetner explains. "He's hitting .358 with a 1.255 OPS at home, compared to .254 on the road, and he's been on a tear—six home runs over his last 10 home games. Merrill Kelly has given up five of his six home runs this season to left-handed batters, who are hitting .328 with a 1.144 OPS against him. Kelly has also been struggling, allowing 12 earned runs in 16 1/3 innings over his last three starts, including two home runs."

For bettors looking to maximize their returns, these picks can be parlayed together for a potential payout of over 130-1 on some of the best sports betting apps. Whether you're a seasoned pro or new to MLB betting, these insights add an extra layer of excitement to the game. So, grab your favorite team gear, settle in, and get ready for a night of long balls and big hits—because Friday's matchups are shaping up to be unforgettable.