Thanksgiving just got a whole lot spicier for Buffalo Bills fans. According to multiple reports, the Bills are set to host the Kansas City Chiefs on Thanksgiving night in what would be the first-ever home Thanksgiving game in franchise history. Kickoff is scheduled for 8:20 p.m. ET on Thursday, Nov. 26, on NBC, capping off the NFL's holiday tripleheader.

This showdown brings one of the league's most intense rivalries to Orchard Park, and the stakes couldn't be higher. The Bills have owned the regular-season matchups against the Chiefs, going a perfect 5-0 over the last six seasons. Last year's 28-21 victory was a masterclass from Josh Allen, who threw for a touchdown and ran for two more, while the defense limited Patrick Mahomes to just 15-of-34 passing with an interception and three sacks. But when it comes to the playoffs, the script flips. Kansas City has ended Buffalo's Super Bowl dreams four times in the last six years—in 2020, 2021, 2023, and 2024.

Adding to the drama, Mahomes is currently recovering from a torn ACL suffered in December, though he's expressed optimism about returning for the start of the season. If he's healthy, this Thanksgiving night clash could be another chapter in a rivalry that already feels destined for prime time.

The game also serves as a national showcase for the brand-new Highmark Stadium, which will host its first regular-season game earlier in the season when the Bills take on the Detroit Lions in Week 2. Buffalo's Thanksgiving history is solid—they're 6-4-1 all-time on the holiday—but every one of those games was on the road. This year, they'll finally get to feast at home.

The rest of the reported Thanksgiving slate includes the Chicago Bears at the Detroit Lions and the Philadelphia Eagles at the Dallas Cowboys. But for Bills Mafia, the main course is clear: a historic home game against their biggest rival, with a side of playoff redemption on the line.