76ers vs. Knicks odds, prediction, time: 2026 NBA playoff picks, Game 2 best bets from proven model

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76ers vs. Knicks odds, prediction, time: 2026 NBA playoff picks, Game 2 best bets from proven model

76ers vs. Knicks odds, prediction, time: 2026 NBA playoff picks, Game 2 best bets from proven model

SportsLine's model reveals its New York Knicks vs. Philadelphia 76ers Game 2 picks

76ers vs. Knicks odds, prediction, time: 2026 NBA playoff picks, Game 2 best bets from proven model

SportsLine's model reveals its New York Knicks vs. Philadelphia 76ers Game 2 picks

The hardwood stage is set for another electrifying chapter in one of the NBA's most storied rivalries. The Philadelphia 76ers and New York Knicks are back at it in Game 2 of the Eastern Conference second round, and the stakes couldn't be higher. After a dominant 137-98 statement win in Game 1, the Knicks are looking to tighten their grip on the series, while the Sixers are desperate to even the score at Madison Square Garden.

Game 2 tips off Wednesday at 7 p.m. ET, with the Knicks entering as 6.5-point favorites. The total points line sits at 215.5. New York, the No. 3 seed, has the home-court advantage locked in, but Philadelphia—led by MVP-caliber center Joel Embiid—knows they can steal one on the road. The regular-season series was a dead heat, with each team sweeping the other on their home floor, so the Sixers have plenty of reason to believe a bounce-back is within reach.

That said, the Knicks are rolling. Jalen Brunson has been a playoff force, and New York's defense suffocated the Sixers in Game 1, holding them to just 98 points. For Philadelphia to flip the script, they'll need to find their offensive rhythm early and keep the Knicks from running away with the pace. Expect a much tighter contest than the series opener.

For bettors and basketball fans alike, the key question is whether the Sixers can cover the spread or if the Knicks will continue their march. The over/under is also worth watching—Game 1 soared past the total, but oddsmakers have adjusted. Will the scoring slow down, or can both teams light it up again?

With the energy of a packed Garden and everything on the line, Game 2 promises to be a must-watch. Whether you're rooting for the underdog or the home favorite, this is playoff basketball at its finest.

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